M.Sc in Microbiology - Tribhuvan University

M. Sc. Microbiology programme was started at Tribhuvan University in 1990 for the first time in Nepal at the Central Department of Microbiology, Tribhuvan University, Kirtipur. The course structure of the programme was changed in 1999 and revised in 2008 and 2009. However, the course was based on the annual examination system. The course structure of the programme was changed into semester system in 2013.Therefore, this is a revised semester system credit based course curriculum to make it more competitive and research oriented as per international trend.

M.Sc Microbiology course is divided into four semesters within two academic years. The present curriculum is designed to upgrade M.Sc. microbiology degree of Institute of Science and Technology, Tribhuvan University to international level in accordance to current advances in microbiology. The new curriculum emphasizes on research based teaching learning practice. 

The present curriculum aims to produce qualified microbiologists, molecular biologists, researchers and scientists as per national and international demand. The master's degree holders will be able to use skills of modern molecular biology techniques in basic science research or in applied research areas of microbiology. The graduates will be able to work as a qualified scientist for investigating the potential uses of microorganisms to produce antibiotics, antibodies, steroids, vaccines, hormones and other products of microbial origin. The master's degree holders will be able to work as a microbiologist and research scientist in the laboratories for monitoring, identifying and helping to control infectious diseases. They will also be able to work as qualified researchers and scientists in the institutions related to food production, crop protection and soil fertility.

Each year around 300 students are enrolled in MSc Microbiology program of Tribhuvan University which is the highest enrollment in biological sciences and also in top of all affiliations given to private colleges of Tribhuvan University, Institute of Science and Technology.

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Admission criteria

  1. Students must attend and pass the entrance examination.
  2. Pass mark for the entrance examination is 35%.
  3. Students will be enrolled on the basis of merit. Merit list is published on the basis of both marks obtained in Bachelor level and entrance examination.
    Merit list: = 20% (marks obtained in B.Sc) + 80 % (marks secured in entrance examination)

In Central department and constituent campuses of Tribhuvan University; out of total available seats 80% seats will be filled from free competition and 20% from reserved (inclusive) category.

Students who want to compete from proportional representation category must fulfilled following criteria.

  • Passed SLC from community schools
  • Students who are permanent resident of backward region must have passed SLC from the same region
  • Students must have passed Bachelor level from constitutent campus of Tribhuvan University or Community campuses.

Documents needed:

If any seats remain vacant in the inclusive/reserved category; remaining seats will be fulfilled from the merit list of free competition.

Salient features

Teaching Methodology

The general teaching methodology of the program includes interactive lectures, students’ presentations, case studies and projects.

Language of Instruction: English

Hours of Instruction: 

Total Credits: 64 credits within four semesters.

1. Working days: 90 days in a semester
2. Class hours:

  • Theory: One credit is equivalent to 15 teaching hours in a semester. One theory paper of 1 credit will have 1 hour of lecture per week.
  • Practical: One credit is equal to 60 practical hours in a semester. One practical paper of 1.5 or 1 credit will have 4 hours of practical per week.


Student should be regular in their classes. Students failing to maintain 80% presence are not allowed to appear in the semester-end examinations and regarded as “not qualified”. However, in case of serious illness the students with 70% attendance will be given chance to appear in the semester-end exam. In this case students have to submit an authorized medical certificate.

Normal and Maximum Duration of Study

The normal duration and the maximum duration for the completion of the requirements for the program is as follows:

  1. Normal duration 24 months (4 academic semesters)
  2. Maximum duration 60 months (10 academic semesters)

Students failing to complete the requirements in 60 months have to re-enroll.


Students must pass the internal assessment in order to appear for the final examination. There will be two internal assessments which will count as 40% internal evaluation. The pass marks for theory is 50% and practical subjects are 50%. Institute of Science and Technology, Tribhuvan University will conduct semester examination. The final semester examination of 1 credit theory subject will have 1 hour of duration (3C ≈ 3 hrs) and internal assessment will have one hour of duration for all subjects.


Total marks obtained in internal and semester-end exams shall be graded on absolute bases. The performance of a student shall be made on four point scale ranging from 0 to 4 grades. A student must secure a minimum Grade Point Average (GPA) of 2.7 or Grade B minus (B-) in each course.

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The candidates with Bachelor’s Degree in Microbiology from Tribhuvan University or equivalent degree recognized by Tribhuvan University can apply for admission. Each applicant should appear and pass entrance examination conducted by the Central Department of Microbiology. The enrollment is based on merit marks secured by the student in entrance (80%) and B Sc Microbiology (20%).. The candidates failed to get minimum qualifying marks/pass marks is denied admission.

Curricular structure

The entire course of M.Sc Microbiology is divided into four semesters within two academic years. 

The first semester course covers the disciplines of General/Advances in Microbiology, Immunology, Microbial Genetics, Microbial Biochemistry and Biotechnology and practical on these courses. 

The second semester offers track selection among four different disciplines of microbiology for specialization. The four disciplines from second semester include Medical Microbiology, Public Health Microbiology, Food and Industrial Microbiology and Agriculture Microbiology with their practical courses. 

In the second semester, students are required to choose one of the four different disciplines offered and continue with it through the third and fourth semesters. Students are not allowed to change the discipline once they have chosen it. The selection of discipline of microbiology may depend upon the facilities available at the department. To gain exposure, students are encouraged to go for excursion after the second semester.

The fourth semester is completely research oriented that includes internship based on selected track and dissertation. 


M.Sc Microbiology (Semester System) Revised Curriculum 2017.pdf

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