The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2018 with one half to Frances H. Arnold “for the directed evolution of enzymes” and the other half jointly to George P. Smith and Sir Gregory P. Winter “for the phage display of peptides and antibodies.”
The power of evolution is revealed through the diversity of life. The 2018 Nobel Laureates in Chemistry have taken control of evolution and used it for purposes that bring the greatest benefit to humankind. Enzymes produced through directed evolution are used to manufacture everything from biofuels to pharmaceuticals. Antibodies evolved using a method called phage display can combat autoimmune diseases and, in some cases, cure metastatic cancer.
This year’s Nobel Laureates have been inspired by the power of evolution and used the same principles – genetic change and selection – to develop proteins that solve humankind’s chemical problems.